InSyBio Team

Labros Digonis


Labros is responsible for strategy, financial and operations planning.

Labros is a Naval Architect and Marine Engineer by education, MBA from Warwick, UK and Advanced Management from INSEAD, futures & options Certified Trader by CFTS, US. He has over 27 years of experience in top-management positions in multibillion Groups and in several Industries, in the fields of Technology, Finance, Healthcare & Consulting. He has been a successful entrepreneurial manager developing startups with business spanning many countries. Created and managed to global success at least two world class technology products (Finance & Energy Management respectively).

Dr. Christos Alexakos


Christos is responsible for the day-to-day management, the operation supervising and the financial management.

Christos is a Computer Engineer with PhD in Computer Science and Engineering from University of Patras (Greece). He is a highly experienced programmer and software architect and he has worked in many ICT projects for both public and private sector since 2001. The last 5 years he was worked as IT Team Leader and Project Manager in various Development and R&D ICT Projects. Furthermore, he was a collaborating Senior Computer Engineering with Pattern Recognition Laboratory of Univ. of Patras, Medical Physics Department of Univ. of Patras, Industrial Systems Institute and Computer and Technology Institute. His research refers to Knowledge Management for Information Systems Integration with applications in the areas of enterprise integration, e-learning, medical physics and bioinformatics.

Dr. Konstantinos Theofilatos

CTO & Technical Sales Manager

Konstantinos is responsible for the marketing and sales management.

Konstantinos is a Computer Engineer with PhD in Computer Science and Engineering from University of Patras (Greece). His PhD studies were on the «Development and Application of Computational Intelligence techniques for the analysis of protein data». His research interests include computational intelligence, bioinformatics, data mining, web technologies and time series forecasting. So far he has made 14 publications in academic journals and more than 25 publications in international conference proceedings, two of which have been awarded as Best Papers. Furthermore, he has worked as a Senior Computer Engineer in five R&D projects.

Aigli Korfiati

Product Development & Support Manager

Aigli is responsible for the product development and support department.

Aigli is a Computer Engineer and MSc student on Computer Sciences. Since 2010 she has focused on Bioinformatics applications, having publications on the prediction of miRNA genes and miRNA target genes. For her research on the prediction of Human miRNA Target Genes, she has won the Best Price Award at SETN 2012 conference. Her research interests include Computational Biology and Bioinformatics, Computational Intelligence, Artificial Intelligence and Parallel Algorithms. Moreover, she has participated on the development of a web-based task-specific Information System and the application of parallel algorithms on cloud and cluster environments.

Mackenzie Hastings

Director of Business Development

Mackenzie is responsible for business development in North America

Mackenzie is a graduate of Washington State University where she studied neuroscience and psychology, received a Bachelor of Science degree and was an active member of the WSU Honors College. She participated in nationally funded; multi-state research projects that examined the effects of Atrazine induced epigenetic transgenerational inheritance of disease, lean phenotype and sperm epimutation pathology biomarkers. Under the department of Integrative Physiology and Neuroscience she ran her own research project, using the 4-core genotype, which examined the effects of Kdm5c gene mutations with varying testosterone levels on anxiety and aggression. Her other research interests include Mental Health, Cancer, Neurodegenerative Diseases and Medical Biotechnology.

Ioanna Papanikolaidi

Full Stack Web Developer

Ioanna is responsible for the design and implementation of InSyBio Suite’s GUI

Ioanna is a Computer Engineer from Department of Computer Engineering & Informatics from University of Patras (Greece) and holds a master degree on Medical Physics from University of Patras. During her working experience since 2012 as a Full Stack Web Developer earned experience and skills as she been involved in many large-scale web applications for the Greek Ministry of Education facing the importance of time management and open communication. Bioinformatics and medical physics were always on her interests that’s why she participated in “Intelligence system for the Prediction, Diagnosis, Care and Support of patients with Mental disorders (EnNoisis)” as a researcher and software engineer and attended a seminar Informatics in Medicine during her Erasmus Studies in Karlsruhe Institute of Technology (KIT).

Lampros Androutsos

Scientific Programmer

Lampros is responsible for the implementation of biological data analysis algorithms

Lampros is a computer engineer from the Department of Computer Engineering and Informatics at the University of Patras (Greece). He is now pursuing a MSc degree in Informatics for Life Sciences with specialization in Bioinformatics at the School of Medicine, University of Patras. After successfully completing his three-month internship at InSyBio, as a Python backend developer, where he implemented deep neural networks in InSyBio’s biomarkers discovery pipeline, he is the main machine learning/backend developer since August 2021. Since September 2021, he is also working as a junior data analyst in Virtuous Horizon 2020 funded project ( having done placements in Politecnico di Torino, Universidad de Granada and SUPSI – Scuola universitaria professionale della Svizzera italiana.

Scientific Advisory Committee

Dr. Seferina Mavroudi


Doctor Seferina Mavroudi is a lecturer in the Department of Social Work of the TEI of Patras and an adjunct lecturer (407/80) in the Department of Computer Engineering and Informatics of the University of Patras, Greece. Her research interests include computational intelligence, bioinformatics, and scientific computing. Doctor Seferina Mavroudi graduated in 1998 from the Department of Electrical and Computer Engineering, School of Engineering of the Aristotles University of Thessaloniki. In 2000 she received a Master’s degree from the European Postgraduate Program on Biomedical Engineering, organized by the Faculty of Medicine of the University of Patras, the Faculty of Mechanical Engineering and the Faculty of Electrical and Computer Engineering of the National Technical University of Athens, in collaboration with more than 20 European Universities. In the same program, in February of the year 2003 she completed her Ph.D. Thesis with title “Development of advanced computational intelligence models for complex bioinformatics – and biosignal processing applications”. During her phd studies she visited the Bioinformatics Center of the University of Pennsylvania as a visiting researcher. She has 40 publications in international scientific journals, proceedings of international conferences and book chapters. Her research work has earned 188 citations and H-index: 6.

Dr. George Georgiou

Scientific Advisor

Dr. George Georgiou is a Professor, Laura Jennings Turner Chair in Engineering at the University of Texas, Austin. He received his B.Sc. from the University of Manchester, U.K. and Ph.D. from Cornell. His research is focused on understanding the serological antibody repertoire (as well as the BCR and TCR repertoires) in human health and disease and on the discovery and preclinical development of enzyme and antibody therapeutics for cancer and for inborn errors of metabolism. Professor Georgiou was elected to the National Academy of Engineering (2005), National Academy of Medicine (2011) and the American Academy of Arts and Sciences (2016). He is also a Fellow of the American Institute for Biological and Medical Engineers (AIMBE), the American Academy of Microbiology and the American Association for the Advancement of Science (AAAS). He is the author of 250 research publications and co-inventor of 105 issued or pending US patents, more than 65% of which (comprising 24 distinct technology suites) have been licensed to 27 pharma & biotech companies. In 2014, Dr. Georgiou was selected as one of the top 20 Translational Researchers by Nature Biotechnology.

Dr. Nicholas Peppas

Scientific Advisor

Dr. Nicholas Peppas is the Fletcher Pratt Chaired Professor of Chemical Engineering, Biomedical Engineering and Pharmacy at the University of Texas at Austin. He is a world leader in biomaterials, controlled drug delivery and bionanotechnology. He received a Dipl. Eng. from NTU Athens (1971) and a Sc. D. from MIT (1973). Dr Peppas has published more than 1,025 refereed publications, 350 proceedings and 320 abstracts, and is the inventor of 35 US and international patents. He is the coauthor or coeditor of 31 books and volumes, including the classic, three-volume Hydrogels in Medicine and Pharmacy (CRC Press, 1987), a standard reference in the field of biomaterials with more than 3,000 citations, the monograph Pulsatile Drug Delivery, (WSGS, Stuttgart, 1993), two books on Biopolymers (Springer, 1994), the monograph Physicochemical and Cellular Foundations of Biomaterials Science (Academic Press, 2004), the book Intelligent Therapeutics: Biomimetic Systems and Nanotechnology in Drug Delivery (Elsevier, 2004) and his new monograph Nanotechnology in Therapeutics (Horizon Press, 2007). His pioneering contributions have received more than 28,000 citations making him one of the most cited chemical or biological scientists in the world and one of the three most cited Biomedical Engineers. Of particular note is his lifetime effort to rationalize the design and development of biomaterials, drug delivery systems and medical devices. This has led to the development of the mathematical and physicochemical foundations of these fields including several theories and equations, widely used now in Biomedical Engineering. These include the Peppas equation (for the analysis of the abnormal and highly non-Fickian release and delivery of drugs, peptides and proteins from controlled release devices), the Peppas-Merrill equation (for the analysis of protein transport through biomedical membranes), the Brannon-Peppas theory (the first theory to analyze the behavior of intelligent, ionic gels in multicomponent biological fluids), the Huang-Peppas interpenetration theory of tethered structures across biological tissues, and the Peppas-Ritger correlation which has more than 1,000 citations in the last 15 years. His modeling, biomaterials, cellular and drug delivery research has been funded continuously since 1980 by NIH and since 1978 by NSF.

Dr. Constantinos Stathopoulos

Scientific Advisor

Dr. Constantinos Stathopoulos is Professor of Biochemistry since 2014 and leader of the RNA Biology group at the School of Medicine of the University of Patras. He received his BSc in Biology from the University of Patras (1991) and his PhD from the School of Medicine of the same university (1996). He joined Yale University (USA) as Postdoctoral Research Associate (1998-2002) and upon his return, he was first elected Assistant Professor at the University of Thessaly (2002-2009) and then Associate Professor at the University of Patras, School of Medicine (2009-2014). The work of his group is focused on various aspects of RNA biology including RNA catalysis, biogenesis and metabolism, RNA-protein interactions and RNA-mediated regulation of gene expression and protein synthesis, with focus on the role small and long non-coding RNAs in development and diseases, including cancer. His work has been published in highly esteemed journals (Science, PNAS, TiBS, NAR, RNA, RNA Biology, etc) and has been or is funded by major international and national agencies (GSRT-ARISTEIA, FP7, Fondation Santé, etc). He has co-edited 3 special issues on the regulatory role of non-coding RNAs and since 2015 he is member of the editorial board of International Journal of Molecular Biosciences (IF: 3.2; RNA section). He has served as reviewer for more than 30 international peer-reviewed journals, national and international grant agencies and boards. His international collaborations include researchers from major RNA centers in Europe (University of Strasbourg, France) and USA (NIH-NIDDK RNA Molecular Biology Laboratory, Yale University, Ohio State University).

Dr. Alexandros Georgakilas

Scientific Advisor

Dr. Alexandros Georgakilas is an Assistant Professor in the Physics Department of the National Technical University of Athens and the director of the Biophysics/DNA damage and Repair Lab. He received his bachelor’s degree in Physics with Honors at the University of Athens, Athens, Greece in 1992. He pursued post-graduate studies in molecular and cellular biology at the Institute of Biology, NCSR “Demokritos” in 1993. Following post graduate studies, Dr. Georgakilas received his Doctorate in Radiation Biology with Honors on the “Effects of a-Particles radiation on mammalian DNA”, Biology Department at the University of Athens, Greece in 1999. Subsequently, Dr. Georgakilas was a post-doctoral research associate in the Institute of Biology, NCSR “Demokritos” (1999-2000) and in the Department of Physics, Health and Medical Physics Group, Athens, Greece (2000-2001). Additionally, at the Brookhaven National Laboratory, Dr. Georgakilas completed post-doctoral research as an associate in the Biology Department from 2001-2003 under the supervision of Dr. Betsy Sutherland. Over recent years, Dr. Georgakilas’ has developed a reliable methodology for the study of clustered DNA lesions at the cellular or tissue level using human or bacterial DNA repair enzymes based on the pioneering work of Dr. B. Sutherland. There are limited data on the use of the DNA damage molecular assays for the detection of bistranded non-double strand break (DSB) oxidative clustered DNA lesions (OCDLs) in vitro or in vivo. Dr. Georgakilas work has provided a novel adaptation of neutral single cell gel electrophoresis (Comet assay) or pulsed field gel electrophoresis to measure these unique types of lesion and their repair. Thus far, Dr. Georgakilas’ research has contributed to the identification of novel DNA repair pathways for OCDLs, as well as uncovering different strategies that these mutagenic and repair resistant lesions are processed by the cell or human tissue. His work has been published in more than 80 peer-review high impact papers and he has more than 4000 citations. By this way, meaningful insights can be discovered for the biological and clinical application of DNA damage clusters. His interests are in the fields of biophysical analysis of DNA damage, biopolymers, oxidative stress and role of clustered DNA damage in carcinogenesis.

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