InSyBio Suite Version 3.2 is released including an integrated workflow and toolbox for single-cell RNA-sequencing analysis

Single-cell RNA sequencing is a powerful genomic method used to detect and analyze RNA molecules in biological samples at a single-cell level. It has proven successful in studying cell composition, proliferation, and migration. However, analyzing the data presents challenges due to standardization issues, data scarcity, and difficulties in integrating datasets with other sequencing technologies.

The new version of InSyBio Suite introduces new functionalities and toolboxes within the InSyBio ncRNAseq tool for streamlining and optimizing the processing of single-cell RNA-sequencing data and performing all required analyses to facilitate the discovery of biomarkers, cell trajectories, cell-cell communication patterns overcoming the challenges of existing workflows and tools.

In particular, the following functionalities are enabled/supported in the new version of InSyBio ncRNAseq tool:

  • optimized analysis from raw data simplifying the process and ability to be run by non-bioinformatics experts.
  • Efficient integration of multiple scRNAseq datasets, removing efficiently the technical biases and maintaining biological variability.
  • Cell-deconvolution of bulk transcriptomics and proteomics data using scRNAseq data.
  • Discovery and documentation of cell-cell communication patterns using CellChat workflow.
  • Discovery of single-cell trajectories and RNA-velocity patterns using scVelo workflow
  • Custom figure preparation and documented bioinformatics analysis integrated with additional tools of InSyBio Suite for biomarker discovery, network and AI/ML analysis.

The CEO of InSyBio, Labros Digonis, stated: “In the past 5 years, scRNAseq data have been extensively used in the literature but their analysis is difficult, demanding and it is very easy to get misleading results if not conducted by a coding and bioinformatics expert. In line with our company’s priorities, the new version of InSyBio Suite democratizes the use of such data by non-bioinformatics experts allowing the people who generate the data to perform elaborate analytics and get the most out of their data using our user-friendly, web-based platform.”

Read more details about this tool in the updated InSyBio ncRNAseq’s user manual: InSyBio-ncRNASeq-Manual-v3.2.

InSyBio is offering a one-month free license to use InSyBio Suite including the new version of InSyBio ncRNAseq tool. Request your free trial now by completing a simple form at: Get a free one month license of InSyBio Suite.

About InSyBio. InSyBio is an international pioneer biotechnology company revolutionizing the medical field through targeted biomarker discovery, highly accurate predictive analytics and the development of personalization tests for drugs. Its solutions provide the R&D departments of Pharma and Research Institutes with the means to meet their most challenging research and innovation goals. This is done through a sophisticated, software-as-a-service, machine learning platform which comprehensively integrates multi-omics and clinical data, thus reducing the number of samples and additional validation experiments needed. Since 2013, InSyBio has worked with hundreds of academics, large and small companies, hospitals, and research centres allowing them to succeed in their biomarker discovery tasks with an increase of at least 10% in predictive accuracy and a decrease of at least 80% in overall time and cost.

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